Two new phenylpropanoid glycosides from the aerial parts of Lespedeza cuneata

Two new phenylpropanoid glycosides from the aerial parts of Lespedeza cuneata

Two new phenylpropanoid glycosides named cuneataside E (1) and cuneataside F (2), were isolated from the aerial parts of Lespedeza cuneata (Dum. Cours.) G. Don, whose structures were E and Z isomer, respectively. Their structures were elucidated on the basis of comprehensive spectroscopic analysis (...

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Main Authors: Zhang, Chuangfeng, Zhou, Jian, Yang, Jingzhi, Li, Chuangjun, Ma, Jie, Zhang, Dan, Zhang, Dongming
Format: Online
Language:English
Published: Elsevier 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071639/
id pubmed-5071639
recordtype oai_dc
spelling pubmed-50716392016-11-04 Two new phenylpropanoid glycosides from the aerial parts of Lespedeza cuneata Zhang, Chuangfeng Zhou, Jian Yang, Jingzhi Li, Chuangjun Ma, Jie Zhang, Dan Zhang, Dongming Original Article Two new phenylpropanoid glycosides named cuneataside E (1) and cuneataside F (2), were isolated from the aerial parts of Lespedeza cuneata (Dum. Cours.) G. Don, whose structures were E and Z isomer, respectively. Their structures were elucidated on the basis of comprehensive spectroscopic analysis (UV, IR, HR-ESI-MS, 1D and 2D NMR). In in vitro bioassays at 10 μmol/L, compound 1 showed moderate hepatoprotective activity against N-acetyl-p-aminophenol (APAP)-induced toxicity in HeG2 cells. Elsevier 2016-11 2016-06-17 /pmc/articles/PMC5071639/ /pubmed/27818923 http://dx.doi.org/10.1016/j.apsb.2016.05.009 Text en © 2016 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Zhang, Chuangfeng
Zhou, Jian
Yang, Jingzhi
Li, Chuangjun
Ma, Jie
Zhang, Dan
Zhang, Dongming
spellingShingle Zhang, Chuangfeng
Zhou, Jian
Yang, Jingzhi
Li, Chuangjun
Ma, Jie
Zhang, Dan
Zhang, Dongming
Two new phenylpropanoid glycosides from the aerial parts of Lespedeza cuneata
author_facet Zhang, Chuangfeng
Zhou, Jian
Yang, Jingzhi
Li, Chuangjun
Ma, Jie
Zhang, Dan
Zhang, Dongming
author_sort Zhang, Chuangfeng
title Two new phenylpropanoid glycosides from the aerial parts of Lespedeza cuneata
title_short Two new phenylpropanoid glycosides from the aerial parts of Lespedeza cuneata
title_full Two new phenylpropanoid glycosides from the aerial parts of Lespedeza cuneata
title_fullStr Two new phenylpropanoid glycosides from the aerial parts of Lespedeza cuneata
title_full_unstemmed Two new phenylpropanoid glycosides from the aerial parts of Lespedeza cuneata
title_sort two new phenylpropanoid glycosides from the aerial parts of lespedeza cuneata
description Two new phenylpropanoid glycosides named cuneataside E (1) and cuneataside F (2), were isolated from the aerial parts of Lespedeza cuneata (Dum. Cours.) G. Don, whose structures were E and Z isomer, respectively. Their structures were elucidated on the basis of comprehensive spectroscopic analysis (UV, IR, HR-ESI-MS, 1D and 2D NMR). In in vitro bioassays at 10 μmol/L, compound 1 showed moderate hepatoprotective activity against N-acetyl-p-aminophenol (APAP)-induced toxicity in HeG2 cells.
publisher Elsevier
publishDate 2016
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071639/
_version_ 1613690521449922560

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