An essential role for IL-2 receptor in regulatory T cell function

An essential role for IL-2 receptor in regulatory T cell function

Regulatory T (Treg) cells, expressing abundant amounts of the IL-2 receptor (IL-2R), are reliant on IL-2 produced by activated T cells. This feature implied a key role for a simple network based on IL-2 consumption by Treg cells in their suppressor function. However, congenital deficiency in IL-2R r...

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Bibliographic Details
Main Authors: Chinen, Takatoshi, Kannan, Arun K., Levine, Andrew G, Fan, Xiying, Klein, Ulf, Zheng, Ye, Gasteiger, Georg, Feng, Yongqiang, Fontenot, Jason D., Rudensky, Alexander Y.
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071159/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071159/

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