An Abbreviated Protocol for In Vitro Generation of Functional Human Embryonic Stem Cell-Derived Beta-Like Cells

The ability to yield glucose-responsive pancreatic beta-cells from human pluripotent stem cells in vitro will facilitate the development of the cell replacement therapies for the treatment of Type 1 Diabetes. Here, through the sequential in vitro targeting of selected signaling pathways, we have dev...

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Bibliographic Details
Main Authors: Massumi, Mohammad, Pourasgari, Farzaneh, Nalla, Amarnadh, Batchuluun, Battsetseg, Nagy, Kristina, Neely, Eric, Gull, Rida, Nagy, Andras, Wheeler, Michael B.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068782/