Characterization of brain mGluR5 binding in a pilot study of late-life major depressive disorder using positron emission tomography and [11C]ABP688

Characterization of brain mGluR5 binding in a pilot study of late-life major depressive disorder using positron emission tomography and [11C]ABP688

The metabotropic glutamate receptor subtype 5 (mGluR5) has been implicated in the pathophysiology of mood and anxiety disorders and is a potential treatment target in major depressive disorder (MDD). This study compared brain mGluR5 binding in elderly patients suffering from MDD with that in elderly...

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Bibliographic Details
Main Authors: DeLorenzo, C, Sovago, J, Gardus, J, Xu, J, Yang, J, Behrje, R, Kumar, J S D, Devanand, D P, Pelton, G H, Mathis, C A, Mason, N S, Gomez-Mancilla, B, Aizenstein, H, Mann, J J, Parsey, R V
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068588/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068588/

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