Metformin Prevents Renal Stone Formation through an Antioxidant Mechanism In Vitro and In Vivo

Oxidative stress is a causal factor and key promoter of urolithiasis associated with renal tubular epithelium cell injury. The present study was designed to investigate the preventive effects of metformin on renal tubular cell injury induced by oxalate and stone formation in a hyperoxaluric rat mode...

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Bibliographic Details
Main Authors: Yang, Xiong, Ding, Hao, Qin, Zhenbang, Zhang, Changwen, Qi, Shiyong, Zhang, Hongtuan, Yang, Tong, He, Zhen, Yang, Kuo, Du, E, Liu, Chunyu, Xu, Yong, Zhang, Zhihong
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066015/