Metformin Prevents Renal Stone Formation through an Antioxidant Mechanism In Vitro and In Vivo
Oxidative stress is a causal factor and key promoter of urolithiasis associated with renal tubular epithelium cell injury. The present study was designed to investigate the preventive effects of metformin on renal tubular cell injury induced by oxalate and stone formation in a hyperoxaluric rat mode...
Main Authors: | , , , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066015/ |