Amplification of TLO Mediator Subunit Genes Facilitate Filamentous Growth in Candida Spp.

Filamentous growth is a hallmark of C. albicans pathogenicity compared to less-virulent ascomycetes. A multitude of transcription factors regulate filamentous growth in response to specific environmental cues. Our work, however, suggests the evolutionary history of C. albicans that resulted in its f...

Full description

Bibliographic Details
Main Authors: Liu, Zhongle, Moran, Gary P., Sullivan, Derek J., MacCallum, Donna M., Myers, Lawrence C.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065183/