Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals

Macrophages play crucial roles in host defence and tissue homoeostasis, processes in which both environmental stimuli and intracellularly generated metabolites influence activation of macrophages. Activated macrophages are classified into M1 and M2 macrophages. It remains unclear how intracellular n...

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Bibliographic Details
Main Authors: Kimura, Tetsuya, Nada, Shigeyuki, Takegahara, Noriko, Okuno, Tatsusada, Nojima, Satoshi, Kang, Sujin, Ito, Daisuke, Morimoto, Keiko, Hosokawa, Takashi, Hayama, Yoshitomo, Mitsui, Yuichi, Sakurai, Natsuki, Sarashina-Kida, Hana, Nishide, Masayuki, Maeda, Yohei, Takamatsu, Hyota, Okuzaki, Daisuke, Yamada, Masaki, Okada, Masato, Kumanogoh, Atsushi
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064021/