SUMOylated NKAP is essential for chromosome alignment by anchoring CENP-E to kinetochores

SUMOylated NKAP is essential for chromosome alignment by anchoring CENP-E to kinetochores

Chromosome alignment is required for accurate chromosome segregation. Chromosome misalignment can result in genomic instability and tumorigenesis. Here, we show that NF-κB activating protein (NKAP) is critical for chromosome alignment through anchoring CENP-E to kinetochores. NKAP knockdown causes c...

Full description

Bibliographic Details
Main Authors: Li, Teng, Chen, Liang, Cheng, Juanxian, Dai, Jiang, Huang, Yijiao, Zhang, Jian, Liu, Zhaoshan, Li, Ang, Li, Na, Wang, Hongxia, Yin, Xiaomin, He, Kun, Yu, Ming, Zhou, Tao, Zhang, Xuemin, Xia, Qing
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064014/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064014/

Similar Items