Severe Changes in Thymic Microenvironment in a Chronic Experimental Model of Paracoccidioidomycosis

T cell maturation takes place within the thymus, a primary lymphoid organ that is commonly targeted during infections. Previous studies showed that acute infection with Paracoccidioides brasiliensis (Pb), the causative agent of paracoccidioidomycosis (PCM), promotes thymic atrophy that is associated...

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Bibliographic Details
Main Authors: Alves da Costa, Thiago, Di Gangi, Rosária, Thomé, Rodolfo, Barreto Felisbino, Marina, Pires Bonfanti, Amanda, Lumi Watanabe Ishikawa, Larissa, Sartori, Alexandrina, Burger, Eva, Verinaud, Liana
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063316/