Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA

Numerous factors direct eukaryotic ribosome biogenesis, and defects in a single ribosome assembly factor may be lethal or produce tissue-specific human ribosomopathies. Pre-ribosomal RNAs (pre-rRNAs) must be processed stepwise and at the correct subcellular locations to produce the mature rRNAs. Nop...

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Bibliographic Details
Main Authors: Zhang, Jun, McCann, Kathleen L., Qiu, Chen, Gonzalez, Lauren E., Baserga, Susan J., Hall, Traci M. Tanaka
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062617/