Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry

To characterize the extent and impact of ancestry-related biases in precision genomic medicine, we use 642 whole-genome sequences from the Consortium on Asthma among African-ancestry Populations in the Americas (CAAPA) project to evaluate typical filters and databases. We find significant correlatio...

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Bibliographic Details
Main Authors: Kessler, Michael D., Yerges-Armstrong, Laura, Taub, Margaret A., Shetty, Amol C., Maloney, Kristin, Jeng, Linda Jo Bone, Ruczinski, Ingo, Levin, Albert M., Williams, L. Keoki, Beaty, Terri H., Mathias, Rasika A., Barnes, Kathleen C., O'Connor, Timothy D.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062569/