Combination therapy with zoledronic acid and cetuximab effectively suppresses growth of colorectal cancer cells regardless of KRAS status

Targeted molecular therapy is an effective anticancer strategy. Anti‐EGFR monoclonal antibodies such as cetuximab (CTX) have been approved for the treatment of various malignancies, including colorectal cancer (CRC) with wild‐type KRAS. However, their efficacy in patients with KRAS mutations has not...

Full description

Bibliographic Details
Main Authors: Kato, Junko, Futamura, Manabu, Kanematsu, Masako, Gaowa, Siqin, Mori, Ryutaro, Tanahashi, Toshiyuki, Matsuhashi, Nobuhisa, Yoshida, Kazuhiro
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057332/