Three-dimensional reconstruction of single-cell chromosome structure using recurrence plots

Single-cell analysis of the three-dimensional (3D) chromosome structure can reveal cell-to-cell variability in genome activities. Here, we propose to apply recurrence plots, a mathematical method of nonlinear time series analysis, to reconstruct the 3D chromosome structure of a single cell based on...

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Bibliographic Details
Main Authors: Hirata, Yoshito, Oda, Arisa, Ohta, Kunihiro, Aihara, Kazuyuki
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057099/