A Novel Nuclear Function for the Interleukin-17 Signaling Adaptor Protein Act1

In the context of the human airway, interleukin-17A (IL-17A) signaling is associated with severe inflammation, as well as protection against pathogenic infection, particularly at mucosal surfaces such as the airway. The intracellular molecule Act1 has been demonstrated to be an essential mediator of...

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Bibliographic Details
Main Authors: Velichko, Sharlene, Zhou, Xu, Zhu, Lingxiang, Anderson, Johnathon David, Wu, Reen, Chen, Yin
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056742/