Autonomously folded α-helical lockers promote RNAi*

RNAi is an indispensable research tool with a substantial therapeutic potential. However, the complete transition of the approach to an applied capability remains hampered due to poorly understood relationships between siRNA delivery and gene suppression. Here we propose that interfacial tertiary co...

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Bibliographic Details
Main Authors: Guyader, Christian P. E., Lamarre, Baptiste, De Santis, Emiliana, Noble, James E., Slater, Nigel K., Ryadnov, Maxim G.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056365/