Activating and Attenuating the Amicoumacin Antibiotics

The amicoumacins belong to a class of dihydroisocoumarin natural products and display antibacterial, antifungal, anticancer, and anti-inflammatory activities. Amicoumacins are the pro-drug activation products of a bacterial nonribosomal peptide-polyketide hybrid biosynthetic pathway and have been is...

Full description

Bibliographic Details
Main Authors: Park, Hyun Bong, Perez, Corey E., Perry, Elena Kim, Crawford, Jason M.
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055758/