Plate-based diversity subset screening generation 2: an improved paradigm for high-throughput screening of large compound files

High-throughput screening (HTS) is an effective method for lead and probe discovery that is widely used in industry and academia to identify novel chemical matter and to initiate the drug discovery process. However, HTS can be time consuming and costly and the use of subsets as an efficient alternat...

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Bibliographic Details
Main Authors: Bell, Andrew S., Bradley, Joseph, Everett, Jeremy R., Loesel, Jens, McLoughlin, David, Mills, James, Peakman, Marie-Claire, Sharp, Robert E., Williams, Christine, Zhu, Hongyao
Format: Online
Language:English
Published: Springer International Publishing 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055576/