MPS1 kinase as a potential therapeutic target in medulloblastoma

Medulloblastoma is the most common type of malignant brain tumor that affects children. Although recent advances in chemotherapy and radiation have improved outcomes, high-risk patients perform poorly with significant morbidity. Gene expression profiling has revealed that monopolar spindle 1 (MPS1)...

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Bibliographic Details
Main Authors: Alimova, Irina, Ng, June, Harris, Peter, Birks, Diane, Donson, Andrew, Taylor, Michael D., Foreman, Nicholas K., Venkataraman, Sujatha, Vibhakar, Rajeev
Format: Online
Language:English
Published: D.A. Spandidos 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055207/