Identification of the nuclear localisation signal of O-GlcNAc transferase and its nuclear import regulation

Nucleocytoplasmic O-GlcNAc transferase (OGT) attaches a single GlcNAc to hydroxyl groups of serine and threonine residues. Although the cellular localisation of OGT is important to regulate a variety of cellular processes, the molecular mechanisms regulating the nuclear localisation of OGT is unclea...

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Bibliographic Details
Main Authors: Seo, Hyeon Gyu, Kim, Han Byeol, Kang, Min Jueng, Ryum, Joo Hwan, Yi, Eugene C., Cho, Jin Won
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054401/