Analysis of Pathway Activity in Primary Tumors and NCI60 Cell Lines Using Gene Expression Profiling Data

To determine cancer pathway activities in nine types of primary tumors and NCI60 cell lines, we applied an in silico approach by examining gene signatures reflective of consequent pathway activation using gene expression data. Supervised learning approaches predicted that the Ras pathway is active i...

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Bibliographic Details
Main Authors: Feng, Xing-Dong, Huang, Shu-Guang, Shou, Jian-Yong, Liao, Bi-Rong, Yingling, Jonathan M., Ye, Xiang, Lin, Xi, Gelbert, Lawrence M., Su, Eric W., Onyia, Jude E., Li, Shu-Yu
Format: Online
Language:English
Published: Elsevier 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054081/