Evaluation of Six Methods for Estimating Synonymous and Nonsynonymous Substitution Rates

Methods for estimating synonymous and nonsynonymous substitution rates among protein-coding sequences adopt different mutation (substitution) models with subtle yet significant differences, which lead to different estimates of evolutionary information. Little attention has been devoted to the compar...

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Bibliographic Details
Main Authors: Zhang, Zhang, Yu, Jun
Format: Online
Language:English
Published: Elsevier 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054070/