Plasmodium vivax VIR Proteins Are Targets of Naturally-Acquired Antibody and T Cell Immune Responses to Malaria in Pregnant Women

P. vivax infection during pregnancy has been associated with poor outcomes such as anemia, low birth weight and congenital malaria, thus representing an important global health problem. However, no vaccine is currently available for its prevention. Vir genes were the first putative virulent factors...

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Main Authors: Requena, Pilar, Rui, Edmilson, Padilla, Norma, Martínez-Espinosa, Flor E., Castellanos, Maria Eugenia, Bôtto-Menezes, Camila, Malheiro, Adriana, Arévalo-Herrera, Myriam, Kochar, Swati, Kochar, Sanjay K., Kochar, Dhanpat K., Umbers, Alexandra J., Ome-Kaius, Maria, Wangnapi, Regina, Hans, Dhiraj, Menegon, Michela, Mateo, Francesca, Sanz, Sergi, Desai, Meghna, Mayor, Alfredo, Chitnis, Chetan C., Bardají, Azucena, Mueller, Ivo, Rogerson, Stephen, Severini, Carlo, Fernández-Becerra, Carmen, Menéndez, Clara, del Portillo, Hernando, Dobaño, Carlota
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053494/