CRISPR-Cas: biology, mechanisms and relevance

Prokaryotes have evolved several defence mechanisms to protect themselves from viral predators. Clustered regularly interspaced short palindromic repeats (CRISPR) and their associated proteins (Cas) display a prokaryotic adaptive immune system that memorizes previous infections by integrating short...

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Bibliographic Details
Main Authors: Hille, Frank, Charpentier, Emmanuelle
Format: Online
Language:English
Published: The Royal Society 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052741/