Biochemical and structural characterization of DNA ligases from bacteria and archaea
DNA ligases seal breaks in DNA using a co-factor that supplies adenylate for the reaction. We review biochemical and structural characterization of DNA ligases from bacteria and archaea, highlighting novel co-factor variants that act as inhibitors and/or non-natural substrates of the enzymes.
| Main Authors: | , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Portland Press Ltd.
2016
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052709/ |