Involvement of the NLRC4-Inflammasome in Diabetic Nephropathy

Diabetic nephropathy (DN) is the leading cause of end-stage kidney disease worldwide but current treatments remain suboptimal. The role of inflammation in DN has only recently been recognized. It has been shown that the NLRP3-inflammasome contributes to DN development by inducing interleukin (IL)-1β...

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Bibliographic Details
Main Authors: Yuan, Fang, Kolb, Ryan, Pandey, Gaurav, Li, Wei, Sun, Lin, Liu, Fuyou, Sutterwala, Fayyaz S., Liu, Yinghong, Zhang, Weizhou
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051905/