Hierarchical phosphorylation of apical membrane antigen 1 is required for efficient red blood cell invasion by malaria parasites

Hierarchical phosphorylation of apical membrane antigen 1 is required for efficient red blood cell invasion by malaria parasites

Central to the pathogenesis of malaria is the proliferation of Plasmodium falciparum parasites within human erythrocytes. Parasites invade erythrocytes via a coordinated sequence of receptor-ligand interactions between the parasite and host cell. One key ligand, Apical Membrane Antigen 1 (AMA1), is...

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Bibliographic Details
Main Authors: Prinz, Boris, Harvey, Katherine L., Wilcke, Louisa, Ruch, Ulrike, Engelberg, Klemens, Biller, Laura, Lucet, Isabelle, Erkelenz, Steffen, Heincke, Dorothee, Spielmann, Tobias, Doerig, Christian, Kunick, Conrad, Crabb, Brendan S., Gilson, Paul R., Gilberger, Tim W.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048298/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048298/

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