Structural studies of the N-terminal fragments of the WW domain: Insights into co-translational folding of a beta-sheet protein

Nascent proteins fold co-translationally because the folding speed and folding pathways are limited by the rate of ribosome biosynthesis in the living cell. In addition, though full-length proteins can fold all their residues during the folding process, nascent proteins initially fold only with the...

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Bibliographic Details
Main Authors: Hanazono, Yuya, Takeda, Kazuki, Miki, Kunio
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048162/