Human Adrenocortical Remodeling Leading to Aldosterone-Producing Cell Cluster Generation

Background. The immunohistochemical detection of aldosterone synthase (CYP11B2) and steroid 11β-hydroxylase (CYP11B1) has enabled the identification of aldosterone-producing cell clusters (APCCs) in the subcapsular portion of the human adult adrenal cortex. We hypothesized that adrenals have layere...

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Bibliographic Details
Main Authors: Nishimoto, Koshiro, Seki, Tsugio, Hayashi, Yuichiro, Mikami, Shuji, Al-Eyd, Ghaith, Nakagawa, Ken, Morita, Shinya, Kosaka, Takeo, Oya, Mototsugu, Mitani, Fumiko, Suematsu, Makoto, Kabe, Yasuaki, Mukai, Kuniaki
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046023/