Brachyury as a potential modulator of androgen receptor activity and a key player in therapy resistance in prostate cancer

Prostate cancer (PCa) is the most commonly diagnosed neoplasm and the second leading cause of cancer-related deaths in men. Acquisition of resistance to conventional therapy is a major problem for PCa patient management. Several mechanisms have been described to promote therapy resistance in PCa, su...

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Bibliographic Details
Main Authors: Pinto, Filipe, Pértega-Gomes, Nelma, Vizcaíno, José R., Andrade, Raquel P., Cárcano, Flavio M., Reis, Rui Manuel
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045364/