Betacellulin induces Slug-mediated down-regulation of E-cadherin and cell migration in ovarian cancer cells

Epithelial ovarian cancer is the leading cause of death among gynaecological cancers. Previous studies have demonstrated that epidermal growth factor receptor (EGFR) ligands can induce ovarian cancer cell invasion by down-regulating E-cadherin. Betacellulin is a unique member of the EGF family. It i...

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Bibliographic Details
Main Authors: Zhao, Jianfang, Klausen, Christian, Qiu, Xin, Cheng, Jung-Chien, Chang, Hsun-Ming, Leung, Peter C.K.
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045363/