Role of the B Allele of Influenza A Virus Segment 8 in Setting Mammalian Host Range and Pathogenicity

Role of the B Allele of Influenza A Virus Segment 8 in Setting Mammalian Host Range and Pathogenicity

Two alleles of segment 8 (NS) circulate in nonchiropteran influenza A viruses. The A allele is found in avian and mammalian viruses, but the B allele is viewed as being almost exclusively found in avian viruses. This might reflect the fact that one or both of its encoded proteins (NS1 and NEP) are m...

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Bibliographic Details
Main Authors: Turnbull, Matthew L., Wise, Helen M., Nicol, Marlynne Q., Smith, Nikki, Dunfee, Rebecca L., Beard, Philippa M., Jagger, Brett W., Ligertwood, Yvonne, Hardisty, Gareth R., Xiao, Haixia, Benton, Donald J., Coburn, Alice M., Paulo, Joao A., Gygi, Steven P., McCauley, John W., Taubenberger, Jeffery K., Lycett, Samantha J., Weekes, Michael P., Dutia, Bernadette M., Digard, Paul
Format: Online
Language:English
Published: American Society for Microbiology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044859/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044859/

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