Spermidine Suppresses Age-Associated Memory Impairment by Preventing Adverse Increase of Presynaptic Active Zone Size and Release

Spermidine Suppresses Age-Associated Memory Impairment by Preventing Adverse Increase of Presynaptic Active Zone Size and Release

Memories are assumed to be formed by sets of synapses changing their structural or functional performance. The efficacy of forming new memories declines with advancing age, but the synaptic changes underlying age-induced memory impairment remain poorly understood. Recently, we found spermidine feedi...

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Bibliographic Details
Main Authors: Gupta, Varun K., Pech, Ulrike, Bhukel, Anuradha, Fulterer, Andreas, Ender, Anatoli, Mauermann, Stephan F., Andlauer, Till F. M., Antwi-Adjei, Emmanuel, Beuschel, Christine, Thriene, Kerstin, Maglione, Marta, Quentin, Christine, Bushow, René, Schwärzel, Martin, Mielke, Thorsten, Madeo, Frank, Dengjel, Joern, Fiala, André, Sigrist, Stephan J.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042543/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042543/

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