Production of mycophenolic acid by Penicillium brevicompactum—A comparison of two methods of optimization
•Medium optimization for MPA production using P. brevicompactum by one-factor-at-a-time and CCD methods.•CCD afforded a 40% higher MPA titer than one-factor-at-a-time method.•The titer was nearly 6-fold higher compared to un-optimized medium.
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Elsevier
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042303/ |