Specificity of broad protein interaction surfaces for proteins with multiple binding partners

Analysis of protein-protein interaction networks has revealed the presence of proteins with multiple interaction ligand proteins, such as hub proteins. For such proteins, multiple ligands would be predicted as interacting partners when predicting all-to-all protein-protein interactions (PPIs). In th...

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Bibliographic Details
Main Authors: Uchikoga, Nobuyuki, Matsuzaki, Yuri, Ohue, Masahito, Akiyama, Yutaka
Format: Online
Language:English
Published: The Biophysical Society of Japan (BSJ) 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042157/