Molecular insights into the OGG1 gene, a cancer risk modifier in BRCA1 and BRCA2 mutations carriers

Molecular insights into the OGG1 gene, a cancer risk modifier in BRCA1 and BRCA2 mutations carriers

We have recently shown that rs2304277 variant in the OGG1 glycosidase gene of the Base Excision Repair pathway can increase ovarian cancer risk in BRCA1 mutation carriers. In the present study, we aimed to explore the role of this genetic variant on different genome instability hallmarks to explain...

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Bibliographic Details
Main Authors: Benitez-Buelga, Carlos, Vaclová, Tereza, Ferreira, Sofia, Urioste, Miguel, Inglada-Perez, Lucia, Soberón, Nora, Blasco, Maria A., Osorio, Ana, Benitez, Javier
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041946/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041946/

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