Synthetic lethality in lung cancer and translation to clinical therapies
Lung cancer is a heterogeneous disease consisting of multiple histological subtypes each driven by unique genetic alterations. Despite the development of targeted therapies that inhibit the oncogenic mutations driving a subset of lung cancer cases, there is a paucity of effective treatments for the...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041331/ |