TAZ promotes cell growth and inhibits Celastrol-induced cell apoptosis
TAZ could promote cell proliferation and inhibit Celastrol-induced cell apoptosis. Up-regulation of B-cell lymphoma-2 (Bcl-2), down-regulation of Bcl-2 associated X protein (Bax) and activation of the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) pathway may be the mechanism underlying...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Portland Press Ltd.
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041157/ |