TAZ promotes cell growth and inhibits Celastrol-induced cell apoptosis

TAZ could promote cell proliferation and inhibit Celastrol-induced cell apoptosis. Up-regulation of B-cell lymphoma-2 (Bcl-2), down-regulation of Bcl-2 associated X protein (Bax) and activation of the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) pathway may be the mechanism underlying...

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Bibliographic Details
Main Authors: Wang, Shuren, Ma, Kai, Chen, Lechuang, Zhu, Hongxia, Liang, Shufang, Liu, Mei, Xu, Ningzhi
Format: Online
Language:English
Published: Portland Press Ltd. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041157/