High Stoichiometry Phosphorylation of Talin at T144/T150 or S446 Produces Contrasting Effects on Calpain-mediated Talin Cleavage and Cell Migration
Focal adhesions are large multi-protein complexes that serve as the linkage between extracellular matrix (ECM) and actin cytoskeleton and control the network of signaling cascades underlying cell migration. Talin plays a key role in focal adhesion turnover, and calpain-mediated proteolysis of talin...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Ivyspring International Publisher
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039385/ |