Population Pharmacokinetic Modeling of Tribendimidine Metabolites in Opisthorchis viverrini-Infected Adults

There is a pressing need for alternative treatments against the liver fluke Opisthorchis viverrini. Oral tribendimidine is a promising candidate, but its population pharmacokinetic properties are unknown. Two phase IIa trials were conducted in Laos in O. viverrini-infected adults receiving single or...

Full description

Bibliographic Details
Main Authors: Vanobberghen, Fiona, Penny, Melissa A., Duthaler, Urs, Odermatt, Peter, Sayasone, Somphou, Keiser, Jennifer, Tarning, Joel
Format: Online
Language:English
Published: American Society for Microbiology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038332/