Establishment of ApoE-knockout mouse model of preeclampsia and relevant mechanisms

In the present study, we established an ApoE-knockout mouse model of preeclampsia to examine the role of vascular endothelial injury associated with abnormal lipid metabolism in the pathogenesis of preeclampsia. To establish the ApoE-knockout homozygous (ApoE−/−) and heterozygous (ApoE+/−) mouse mod...

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Bibliographic Details
Main Authors: Sun, Wenjuan, Cui, Baoxia, Hong, Fanzhen, Xu, Yongping
Format: Online
Language:English
Published: D.A. Spandidos 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038201/