Generation of a flexible loop structural ensemble and its application to induced-fit structural changes following ligand binding
Molecular recognition is often mediated by flexible loops that have widely fluctuating structures and are sometimes disordered, but that form particular complex structures following ligand binding. In fact, many loop structures found in the PDB database are too flexible to be determined precisely. A...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Biophysical Society of Japan (BSJ)
2006
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036648/ |