Profile conditional random fields for modeling protein families with structural information

A statistical model of protein families, called profile conditional random fields (CRFs), is proposed. This model may be regarded as an integration of the profile hidden Markov model (HMM) and the Finkelstein-Reva (FR) theory of protein folding. While the model structure of the profile CRF is almost...

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Bibliographic Details
Main Author: Kinjo, Akira R.
Format: Online
Language:English
Published: The Biophysical Society of Japan (BSJ) 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036637/