Cystic fibrosis transmembrane conductance regulator modulators in cystic fibrosis: current perspectives
Mutations of the CFTR gene cause cystic fibrosis (CF), the most common recessive monogenic disease worldwide. These mutations alter the synthesis, processing, function, or half-life of CFTR, the main chloride channel expressed in the apical membrane of epithelial cells in the airway, intestine, panc...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Dove Medical Press
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036583/ |