Establishing a complementary diagnostic for anti-PD-1 immune checkpoint inhibitor therapy

The role of tumor PD-L1 expression was investigated across the nivolumab clinical development program. Phase III nivolumab trials have shown that patients with tumors not expressing PD-L1 may benefit; therefore, testing is not required to select patients for therapy. The Dako PD-L1 IHC 28-8 pharmDx...

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Bibliographic Details
Main Authors: Novotny, J. F., Cogswell, J., Inzunza, H., Harbison, C., Horak, C., Averbuch, S.
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035792/