Sex Differences in Fiber Connection between the Striatum and Subcortical and Cortical Regions

The striatum is an important subcortical structure with extensive connections to other regions of the brain. These connections are believed to play important roles in behaviors such as reward-related processes and impulse control, which show significant sex differences. However, little is known abou...

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Main Authors:	Lei, Xuemei, Han, Zhuo, Chen, Chuansheng, Bai, Lu, Xue, Gui, Dong, Qi
Format:	Online
Language:	English
Published:	Frontiers Media S.A. 2016
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034007/

id	pubmed-5034007
recordtype	oai_dc
spelling	pubmed-50340072016-10-07 Sex Differences in Fiber Connection between the Striatum and Subcortical and Cortical Regions Lei, Xuemei Han, Zhuo Chen, Chuansheng Bai, Lu Xue, Gui Dong, Qi Neuroscience The striatum is an important subcortical structure with extensive connections to other regions of the brain. These connections are believed to play important roles in behaviors such as reward-related processes and impulse control, which show significant sex differences. However, little is known about sex differences in the striatum-projected fiber connectivity. The current study examined sex differences between 50 Chinese males and 79 Chinese females in their fiber connections between the striatum and nine selected cortical and subcortical regions. Despite overall similarities, males showed stronger fiber connections between the left caudate and rostral cingulate cortex, between the right putamen and the lateral orbitofrontal cortex, between the bilateral putamen and the ventro-lateral prefrontal cortex, and between the right caudate and the ventro-lateral prefrontal cortex, whereas females showed stronger fiber connections between the right putamen and the dorsolateral prefrontal cortex, between bilateral caudate and hippocampus, and between the left putamen and hippocampus. These findings help us to understand sex differences in the striatum-projected fiber connections and their implications for sex differences in behaviors. Frontiers Media S.A. 2016-09-23 /pmc/articles/PMC5034007/ /pubmed/27721750 http://dx.doi.org/10.3389/fncom.2016.00100 Text en Copyright © 2016 Lei, Han, Chen, Bai, Xue and Dong. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Lei, Xuemei Han, Zhuo Chen, Chuansheng Bai, Lu Xue, Gui Dong, Qi
spellingShingle	Lei, Xuemei Han, Zhuo Chen, Chuansheng Bai, Lu Xue, Gui Dong, Qi Sex Differences in Fiber Connection between the Striatum and Subcortical and Cortical Regions
author_facet	Lei, Xuemei Han, Zhuo Chen, Chuansheng Bai, Lu Xue, Gui Dong, Qi
author_sort	Lei, Xuemei
title	Sex Differences in Fiber Connection between the Striatum and Subcortical and Cortical Regions
title_short	Sex Differences in Fiber Connection between the Striatum and Subcortical and Cortical Regions
title_full	Sex Differences in Fiber Connection between the Striatum and Subcortical and Cortical Regions
title_fullStr	Sex Differences in Fiber Connection between the Striatum and Subcortical and Cortical Regions
title_full_unstemmed	Sex Differences in Fiber Connection between the Striatum and Subcortical and Cortical Regions
title_sort	sex differences in fiber connection between the striatum and subcortical and cortical regions
description	The striatum is an important subcortical structure with extensive connections to other regions of the brain. These connections are believed to play important roles in behaviors such as reward-related processes and impulse control, which show significant sex differences. However, little is known about sex differences in the striatum-projected fiber connectivity. The current study examined sex differences between 50 Chinese males and 79 Chinese females in their fiber connections between the striatum and nine selected cortical and subcortical regions. Despite overall similarities, males showed stronger fiber connections between the left caudate and rostral cingulate cortex, between the right putamen and the lateral orbitofrontal cortex, between the bilateral putamen and the ventro-lateral prefrontal cortex, and between the right caudate and the ventro-lateral prefrontal cortex, whereas females showed stronger fiber connections between the right putamen and the dorsolateral prefrontal cortex, between bilateral caudate and hippocampus, and between the left putamen and hippocampus. These findings help us to understand sex differences in the striatum-projected fiber connections and their implications for sex differences in behaviors.
publisher	Frontiers Media S.A.
publishDate	2016
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034007/
_version_	1613659128075386880

Sex Differences in Fiber Connection between the Striatum and Subcortical and Cortical Regions

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