Deficits in striatal dopamine release in cannabis dependence

Most drugs of abuse lead to a general blunting of dopamine release in the chronic phase of dependence, which contributes to poor outcome. To test whether cannabis dependence is associated with a similar dopaminergic deficit, we examined striatal and extrastriatal dopamine release in severely cannabi...

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Bibliographic Details
Main Authors: van de Giessen, Elsmarieke, Weinstein, Jodi J., Cassidy, Clifford M., Haney, Margaret, Dong, Zhengchao, Ghazzaoui, Rassil, Ojeil, Najate, Kegeles, Lawrence S., Xu, Xiaoyan, Vadhan, Nehal P., Volkow, Nora D., Slifstein, Mark, Abi-Dargham, Anissa
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033654/