Phosphorylation of Def Regulates Nucleolar p53 Turnover and Cell Cycle Progression through Def Recruitment of Calpain3

Phosphorylation of Def Regulates Nucleolar p53 Turnover and Cell Cycle Progression through Def Recruitment of Calpain3

Digestive organ expansion factor (Def) is a nucleolar protein that plays dual functions: it serves as a component of the ribosomal small subunit processome for the biogenesis of ribosomes and also mediates p53 degradation through the cysteine proteinase calpain-3 (CAPN3). However, nothing is known a...

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Bibliographic Details
Main Authors: Guan, Yihong, Huang, Delai, Chen, Feng, Gao, Ce, Tao, Ting, Shi, Hui, Zhao, Shuyi, Liao, Zuyuan, Lo, Li Jan, Wang, Yingchun, Chen, Jun, Peng, Jinrong
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033581/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033581/

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