Modulatory Effect of 2-(4-Hydroxyphenyl)amino-1,4-naphthoquinone on Endothelial Vasodilation in Rat Aorta

The vascular endothelium plays an essential role in the control of the blood flow. Pharmacological agents like quinone (menadione) at various doses modulate this process in a variety of ways. In this study, Q7, a 2-phenylamino-1,4-naphthoquinone derivative, significantly increased oxidative stress a...

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Bibliographic Details
Main Authors: Palacios, Javier, Cifuentes, Fredi, Valderrama, Jaime A., Benites, Julio, Ríos, David, González, Constanza, Chiong, Mario, Cartes-Saavedra, Benjamín, Lafourcade, Carlos, Wyneken, Ursula, González, Pamela, Owen, Gareth I., Pardo, Fabián, Sobrevia, Luis, Buc Calderon, Pedro
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031853/