IL-18BP is decreased in osteoporotic women: Prevents Inflammasome mediated IL-18 activation and reduces Th17 differentiation

IL-18BP is decreased in osteoporotic women: Prevents Inflammasome mediated IL-18 activation and reduces Th17 differentiation

IL-18BP is a natural antagonist of pro-inflammatory IL-18 cytokine linked to autoimmune disorders like rheumatoid arthritis. However, its role in post menopausal osteoporosis is still unknown. In this study, we investigated the role of IL-18BP on murine osteoblasts, its effect on osteoblasts-CD4+ T...

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Bibliographic Details
Main Authors: Mansoori, Mohd Nizam, Shukla, Priyanka, Kakaji, Manisha, Tyagi, Abdul M, Srivastava, Kamini, Shukla, Manoj, Dixit, Manisha, Kureel, Jyoti, Gupta, Sushil, Singh, Divya
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030484/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030484/

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