A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients

A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients

We wanted to examine tolerability and efficacy of NSI-189, a benzylpiperizine-aminiopyridine neurogenic compound for treating major depressive disorder (MDD). This was a Phase 1B, double blind, randomized, placebo controlled, multiple-dose study with three cohorts. The first cohort received 40 mg q....

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Bibliographic Details
Main Authors: Fava, M, Johe, K, Ereshefsky, L, Gertsik, L G, English, B A, Bilello, J A, Thurmond, L M, Johnstone, J, Dickerson, B C, Makris, N, Hoeppner, B B, Flynn, M, Mischoulon, D, Kinrys, G, Freeman, M P
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030464/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030464/

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